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Findings from a recent study, she said, suggest that the 50 gram glucose challenge test, a test used to screen for gestational diabetes in pregnancy, may represent a promising alternative to HbA1c as a screening test for diabetes or prediabetes (Phillips et al. Diabetologia. 2009;52:1798-1807) because it has been shown to be accurate and can be readily performed during office visits at any time of the day and without a prior fast.
The bottom line is that if you use an HbA1c measurement as a screening test, you'll have a lot of false-negatives and some false-positives," said Mary Rhee, MD, Assistant Professor of Endocrinology at Emory University in Atlanta. And in this day and age when diabetes is a worsening public health epidemic not only in the U.S. but also around the world, we can't afford to end up with more cases of undiagnosed diabetes."

 

Rimonabant (also known as SR141716; trade names Acomplia, Bethin, Monaslim, Remonabent, Riobant, Slimona, Rimoslim, Zimulti, and Riomont) is an anorectic antiobesity drug. It is an inverse agonist for the cannabinoid receptor CB1. Its main effect is reduction in appetite. Rimonabant was the first selective CB1 receptor blocker to be approved for use anywhere in the world.
Citalopram (trade names: Celexa, Cipramil) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has FDA approval to treat major depression, and is prescribed off-label for a number of anxiety conditions.

 

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