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On its own, spironolactone is only a weak diuretic because its effects target the distal nephron (collecting tubule), where urine volume can only be slightly modified; but it can be combined with other diuretics to increase efficacy.
Amoxicillin is susceptible to degradation by b-lactamase-producing bacteria, and so may be given with clavulanic acid to decrease its susceptibility. |
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